NSCI6123 – Molecular Genetics

Module code

NSCI6123

Module title

Molecular Genetics

Prescription

The aim of this course is to provide aakonga with knowledge of the principles and methods of gene technology, and how these may be applied in identified contexts.

NZQA Level

Level 6

NZQA Credits

Delivery method

Web-Enhanced

Learning hours

Total learning hours: 150

Resources required

Content: LO1:
- DNA
- rRNA
- mRNA
- tRNA and snRNA structure
- Physical properties of DNA
LO2:
- DNA structure
- Mode of replication of bacterial chromosomes and plasmids
- The effect of mutagens on nucleic acids
LO3:
- Transcription and translation
- Control of gene expression in bacteria
- The structure of the eukaryotic gene structure
- The use of proteomics and microarrays to analyse gene expression
LO4:
- Natural mechanisms of gene transfer in bacteria including transposons and insertion sequences
- The use of gene transfer techniques for genetic engineering
LO5:
- DNA and RNA purification tecniques for DNA isolation
- The polymerase chain reaction (PCR)
- The mode of action of restriction enzymes and restriction digests
- DNA transformation
LO6:
- Principles of gene cloning techniques (cloning vectors, DNA sequencing, cDNA, DNA libraries, blotting techniques, DNA fingerprinting)
LO7:
- Implications and regulatory framework of gene technologies (modification, DNA sequencing, DNA fingerprinting, and use of personal genomic information by others)
Learning Outcomes: LO1: Describe the structure and physical properties of nucleic acids.
LO2: Interpret gene structure and replication.
LO3: Explain prokaryotic and eukaryote gene expression and control.
LO4: Compare and contrast gene transfer mechanisms.
LO5: Investigate and perform gene cloning and analysis techniques.
LO6: Illustrate with examples teh broad uses and potential of gene technology, and the application in a specific industrial context.
LO7: Explain NZ legislation controlling the use and application of gene technology.
Teaching and Learning Strategy: Learning and teaching activities will employ a range of elements drawn from approved methods to align with the context of the learning (delivery mode, regional specific requirement, etc.) and any particular needs of the group of aakonga.
Assessment Criteria: Assessment portfolio 100%

Assessment activity will employ a range of elements drawn from approved methods to align with the context of the learning (delivery mode, regional specific requirement, etc.) and any particular needs of the group of akonga.
Learning and Teaching Resource: All required and recommended resources are advised to aakonga via course outlines.